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  • Body Fat and its Relationship with Metabolic Syndrome Indicators in Overweight Pre-Adolescents and Adolescents

    Closed for proposals

    Project Type

    Coordinated Research Project

    Project Code

    E43019

    CRP

    853

    Approved Date

    2 September 2005

    Status

    Closed

    Start Date

    15 December 2005

    Expected End Date

    3 June 2011

    Completed Date

    3 June 2011

    Objectives

    To establish the relationship between body mass index (BMI) and body fat and explore their association with indicators of metabolic syndrome in pre-adolescents and adolescents from different ethnic groups.

    Specific objectives

    1. To define the relationship between body mass index (BMI) and body fat in pre-adolescents of 9 years at the first stage of puberty (Tanner Stage 1: T1) and adolescents of 16 years old at the 4th and 5th stages of puberty (T4-5) from different ethnic groups.

    2. To determine the relationship between body fat and insulin, glucose and blood pressure in overweight pre-adolescents and adolescents from different ethnic groups.

    Impact

    Data from this CRP will assist the health policy makers in Member States in their efforts to prevent and control obesity related non-communicable diseases. At the start of the CRP, data was lacking in many Member States, so this data will be a baseline for comparison with future data following interventions. The skills developed in China, Malaysia and Morocco are being utilised in the follow-on CRP E4.30.24, "Nuclear techniques to assess body composition in children and adolescents as a risk factor in the development of chronic diseases". Morocco is a key partner in TC Regional project RAF6042 "Applying Nuclear Techniques to Design and Evaluate Interventions to Reduce Obesity and Related Health Risks", which started in 2012 and involves 12 African Member States. The CSI from Malaysia will be the lead coordinator for a new RAS Regional project for the 2014-2015 cycle "Preventing overweight and obesity, and promoting physical activity among children and adolescents in Asia", which will involve 19 countries in the region; emphasising the importance of the topic, and of synergies between the Technical Cooperation programme and CRP's in nutrition.

    Relevance

    The CRP is highly relevant, as WHO Member States will adopt the Global Monitoring Framework on Noncommunicable Diseases during the World Health Assembly in May 2013. The framework comprises nine global targets and 25 indicators, including one related to adolescent obesity.

    CRP Publications

    Type

    Research Report

    Year

    2012

    Publication URL

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489944/pdf/jhpn0030-0281.pdf

    Description

    KHAN, A.I., et al., Body composition of Bangladeshi children: comparison and development of leg-to-leg bioelectrical impedance equations, J. Health Popul. Nutr. 30 (2012) 281-290.

    Country/Organization

    Bangladesh

    Type

    Research Report

    Year

    2011

    Description

    HOSSEINI-ESFAHANI, F., et al., Trends in risk factors for cardiovascular disease among Iranian adolescents: the Tehran Lipid and Glucose Study, 1999-2008. J. Epidemiol. 21 (2011) 319-328.

    Country/Organization

    Iran

    Type

    Review

    Year

    2011

    Description

    MARTINS, V.J.B. et al., Long-lasting effects of undernutrition, Int. J. Environ. Res. Public Health, 8 (2011) 1817-1846.

    Country/Organization

    Brazil

    Type

    Research Report

    Year

    2010

    Description

    MIRMIRAN, P., et al., Performance of different definitions of metabolic syndrome for children and adolescents in a 6-year follow-up: Tehran Lipid and Glucose Study (TLGS). Diabetes Res. Clin. Pract. 89 (2010) 327-333.

    Country/Organization

    Iran

    Type

    Research Report

    Year

    2009

    Description

    LIU, A., et al., Relationship between anthropometric parameters and lipids profiles (2009) (published in Chinese)

    Country/Organization

    China

    Type

    Research Report

    Year

    2012

    Publication URL

    http://informahealthcare.com/doi/pdf/10.3109/03014460.2012.655776

    Description

    NASREDDINE, L., et al., Obesity is associated with insulin resistance and components of the metabolic syndrome in Lebanese adolescents, Ann. Hum. Biol. 39 (2012) 122-128.

    Country/Organization

    Lebanon

    Type

    Research Report

    Year

    2011

    Description

    CLEMENTE, A.P. et al., índice de massa corporal de adolescentes: compara??o entre diferentes referências, Revista Paulista de Pediatria 29 (2011) 171-177.

    Country/Organization

    Brazil

    Type

    Research Report

    Year

    2012

    Description

    BARZIN, M., et al., The association of anthropometric indices in adolescence with the occurrence of the metabolic syndrome in early adulthood: Tehran Lipid and Glucose Study (TLGS).

    Country/Organization

    Iran

    Type

    Research Report

    Year

    2011

    Publication URL

    http://www.biomedcentral.com/content/pdf/1471-2458-11-500.pdf

    Description

    LIU, A., et al., Ethnic differences in body fat distribution among Asian pre-pubertal children: a cross-sectional multicenter study, BMC Public Health 11 (2011) 500-506.

    Country/Organization

    China

    Type

    Research Report

    Year

    2009

    Description

    SANTOS, C.D.L. et al., Influencia do deficit de estatura nos desvios nutricionais em adolescentes e pré-adolescentes. Revista de Nutri??o 22 (2009) 187-194.

    Country/Organization

    Brazil

    Type

    Research Report

    Year

    2010

    Publication URL

    http://www.karger.com/Article/Pdf/321532

    Description

    NASREDDINE, L., et al., 2010, Metabolic Syndrome and Insulin Resistance in Obese Pre-Pubertal Children in Lebanon: A Primary Health Concern. Ann. Nutr. Metabol. 57 (2010) 135-142.

    Country/Organization

    Lebanon

    Type

    Research Report

    Year

    2011

    Description

    WANG, X. et al., A bioelectrical impedance prediction equation for the assessment of total body water and fat-free mass among Chinese children aged 7-10 year. Chinese Journal of Prevention and Control of Chronic Disease 19 (2011) 441-444.

    Country/Organization

    China

    Type

    Research Report

    Year

    2010

    Description

    LIU, A., et al., Waist circumference cut-off values for the prediction of cardiovascular risk factors clustering in Chinese school-aged children: a cross-sectional study. BMC Public Health 10 (2010) 82-90.

    Country/Organization

    China

    Type

    Research Report

    Year

    2011

    Publication URL

    http://www.nature.com/ejcn/journal/v65/n12/full/ejcn2011122a.html

    Description

    LIU, A., et al., Validation of bioelectrical impedance analysis for total body water assessment against the deuterium dilution technique in Asian children, Eur. J. Clin. Nutr. 65 (2011) 1321-1327.

    Country/Organization

    China

    Type

    Research Report

    Year

    2012

    Publication URL

    http://www.indianpediatrics.net/feb2012/109.pdf

    Description

    JOSE, B. et al., Serum magnesium in overweight children, Indian Pediatr. 49 (2012) 109-112.

    Country/Organization

    India

    Type

    Research Report

    Year

    2012

    Description

    HAMRANI, A., et al., Fat-free mass prediction model for Moroccan adolescents by bioelectrical impedance analysis using deuterium oxide dilution as a reference, Int. J. Body. Comp. Res. 10 (2012) 107-114.

    Country/Organization

    Morocco

    Type

    Research Report

    Year

    2010

    Publication URL

    http://www.hindawi.com/journals/jnume/2010/943070/

    Description

    SANTOS, C.D.L. et al., Adolescents with mild stunting show alterations in glucose and insulin metabolism. J. Nutr. Metabol. (2010), Article ID 943070, 6 pages.

    Country/Organization

    Brazil

    Type

    Research Report

    Year

    2010

    Publication URL

    http://www.ncbi.nlm.nih.gov/pubmed/22691926

    Description

    QUAH, Y.V., POH, B.K., ISMAIL, M.N., Metabolic syndrome based on IDF criteria in a sample of normal weight and obese school children, Malays. J. Nutr. 16 (2010) 207-217.

    Country/Organization

    Malaysia

    Type

    Research Report

    Year

    2012

    Publication URL

    http://www.nature.com/ejcn/journal/v66/n10/full/ejcn201289a.html

    Description

    RAMIREZ, E., et al., Body composition prediction equations based on deuterium oxide dilution method in Mexican children: a national study, Eur. J. Clin. Nutr. 66 (2012) 1099-1103.

    Country/Organization

    Mexico

    Type

    Research Report

    Year

    2010

    Publication URL

    http://www.nature.com/ejcn/journal/v64/n10/full/ejcn2010128a.html

    Description

    CAMPBELL, C.P., et al., Predictors of physical activity energy expenditure in Afro-Caribbean children, Eur. J. Clin. Nutr. 64 (2010) 1093-1100.

    Country/Organization

    Jamaica

    Type

    Research Report

    Year

    2011

    Publication URL

    http://informahealthcare.com/doi/abs/10.3109/17477166.2011.583658

    Description

    POH, B.K., et al., Waist circumference percentile curves for Malaysian children and adolescents aged 6.0-16.9 years, Int. J. Pediatr. Obes. 6 (2011) 229-235.

    Country/Organization

    Malaysia

    Type

    Research Report

    Year

    2011

    Publication URL

    http://journals.cambridge.org/download.php?file=/BJN/BJN106_09/S0007114511001681…

    Description

    LIU, A., et al., Ethnic differences in the relationship between body mass index and percentage body fat among Asian children from different backgrounds, Bri. J. Nutr. 106 (2011) 1390-1397.

    Country/Organization

    China

    Type

    Research Report

    Year

    2012

    Publication URL

    http://www.hindawi.com/journals/jnume/2012/510458/

    Description

    MEHDAD, S., et al., Body mass index, waist circumference, body fat, fasting blood glucose in a sample of Moroccan adolescents aged 11-17 years, J. Nutr. Metabol. (2012) Article ID 510458, 7 pages.

    Country/Organization

    Morocco

    Type

    Research Report

    Year

    2011

    Publication URL

    http://www.jped.com.br/ArtigoDetalhe.aspx?varArtigo=2180&idioma=pt-BR

    Description

    CLEMENTE, A.P. et al., Mild stunting is associated with higher body fat: study of a low-income population, J. Paediatr. (Rio J.) 87 (2011) 138-144.

    Country/Organization

    Brazil

    Type

    Research Report

    Year

    2012

    Publication URL

    http://www.scielo.br/pdf/abc/v98n1/en_aop10911.pdf

    Description

    CLEMENTE, A.P. et al., Mild stunting is associated with higher blood pressure on overweight adolescents, Arq. Bras. Cardiol. 98 (2012) 6-12.

    Country/Organization

    Brazil

    Type

    Research Report

    Year

    2011

    Publication URL

    http://www.biomedcentral.com/content/pdf/1471-2458-11-333.pdf

    Description

    WEE, B.S. et al., Risk of metabolic syndrome among children living in metropolitan Kuala Lumpur: a case control study, BMC Public Health 11 (2011) 333-339

    Country/Organization

    Malaysia

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