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  • Generic approach for the development of genetic sexing strains for SIT applications

    Open for proposals

    Project Type

    Coordinated Research Project

    Project Code

    D44003

    CRP

    2192

    Approved Date

    4 December 2018

    Status

    Active - Ongoing

    Start Date

    27 March 2019

    Expected End Date

    28 March 2025

    Participating Countries

    Argentina
    Australia
    Cameroon
    Canada
    China
    Czech Republic
    France
    Germany
    Greece
    Guatemala
    Israel
    Italy
    Mexico
    Pakistan
    South Africa
    Switzerland
    Thailand
    United Kingdom of Great Britain and Northern Ireland
    United States of America

    Description

    The objective of this CRP is to develop generic approaches for the development of genetic sexing strains for sterile insect technique applications will have the following outputs:

    -Assessment of at least two generic strategies that can be followed to solving the problem of developing GSS: 1) the development of strains that have conditional, sex-specific (female-specific) lethal phenotypes and 2) strains with altered sex determination and development pathways resulting in skewed sex ratios (male-only).

    -Assessment of approaches to successfully implement these strategies and of particular interest are those that are the most widely applicable with respect to the number of target species to which the solution could be implemented with a minimum of research and development.

    -Use of generic approaches to develop genetic sexing strains that reduce research and development time and costs, allowing SIT programs to be more readily developed and implemented against more pest species.

    Objectives

    The main objective of this CRP is the development and evaluation of generic approaches for the construction of genetic sexing strains (GSS) to be used for sterile insect technique (SIT) applications, as part of AW-IPM programs, to control populations of agricultural pests and disease vectors.

    Specific objectives

    To develop generic strategies for the construction of GSS for SIT applications

    To assess the efficiency, applicability and the range of the species transferability of the generic approaches

    To evaluate, at small scale, GSS developed through the generic approaches

    To develop generic strategies for the construction of GSS for SIT applications

    To assess the efficiency, applicability and the range of the species transferability of the generic approaches

    To evaluate, at small scale, GSS developed through the generic approaches

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