Applications of nuclear medicine in Neurology and Neuropsychiatry involve the use of various radiopharmaceuticals which exhibit uptake by central nervous system structures, and are imaged using emission tomography (SPECT or PET).
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Most such radiotracers detect perfusion or metabolic abnormalities of the brain while others interact with basal ganglia receptors, and recently developed compounds bind to abnormal cerebral deposition of proteins such as amyloid. Cerebrovascular disease, epilepsy, and neurodegenerative disorders (especially Alzheimer’s disease) can be successfully evaluated through radionuclide imaging of the brain.