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    Paradoxical pattern in a patient with previous myocardial infarction

    Teaching Case

    Case presentation:

    • Female.
    • 66 y.o.
    • Previous MI.
    • Dyspnea and non-specific chest discomfort.
    • ECG: Q waves V3-V5.
    • Echo: LVEF 48%, apical hypokinesia.
    • Referred for MPS w/ pharmacologic stress.
    • Dipyridamole + rest (2-day protocol), 99mTc-MIBI.
    • Well tolerated, no symptoms, no ECG changes, BP 130/80 mmHg at rest, 120/75 mmHg during the test.

    Teaching points:

    • Myocardial necrosis with a paradoxical pattern (PP) is observed in a few proportion of patients with myocardial necrosis.
    • Necrotic areas with PP have preserved myocardial flow, owing to either patency of the culprit artery, or the presence of collateral circulation to this territory when the artery is occluded.
    • Patients exhibiting a PP on MPS with Tc-99m-labeled tracers have a better prognosis and better LV function than patients with a non-PP pattern in necrotic myocardial regions.
    • PP can also be observed as an artefact in studies with low-count statistics, or if there is dominant attenuation during the stress portion.
    • QC data should be always checked before interpreting MPS.

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